InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SHANK1

Summary

InnateDB Protein

IDBP-693544.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SHANK1

Protein Name

SH3 and multiple ankyrin repeat domains 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000046968

InnateDB Gene

IDBG-641202 (SHANK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030160	GKAP/Homer scaffold activity
GO:0035255	ionotropic glutamate receptor binding

Biological Process

GO:0007616	long-term memory
GO:0008306	associative learning
GO:0030534	adult behavior
GO:0032232	negative regulation of actin filament bundle assembly
GO:0035176	social behavior
GO:0035418	protein localization to synapse
GO:0042048	olfactory behavior
GO:0046959	habituation
GO:0050885	neuromuscular process controlling balance
GO:0050894	determination of affect
GO:0060013	righting reflex
GO:0060997	dendritic spine morphogenesis
GO:0071625	vocalization behavior
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463	positive regulation of excitatory postsynaptic membrane potential

Cellular Component

GO:0005886	plasma membrane
GO:0008328	ionotropic glutamate receptor complex
GO:0016020	membrane
GO:0030425	dendrite
GO:0043005	neuron projection
GO:0043197	dendritic spine
GO:0045211	postsynaptic membrane
GO:0060076	excitatory synapse
GO:0097481	neuronal postsynaptic density

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR001478 PDZ domain
IPR001660 Sterile alpha motif domain
IPR002110 Ankyrin repeat
IPR011510 Sterile alpha motif, type 2
IPR011511 Variant SH3 domain
IPR013761 Sterile alpha motif/pointed domain
IPR020683 Ankyrin repeat-containing domain
IPR021129 Sterile alpha motif, type 1

PFAM