InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GUK1

Summary

InnateDB Protein

IDBP-693545.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GUK1

Protein Name

Guanylate kinase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000036402

InnateDB Gene

IDBG-641212 (GUK1)

Protein Structure

UniProt Annotation

Function

Essential for recycling GMP and indirectly, cGMP.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004385	guanylate kinase activity
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity

Biological Process

GO:0006163	purine nucleotide metabolic process
GO:0016310	phosphorylation
GO:0046939	nucleotide phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR017665 Guanylate kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00625

PRINTS

PIRSF

SMART

SM00072

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P46195