Version 5.4
| Bos taurus Gene: GUK1 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-641212.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | GUK1 | ||||||||||||
| Gene Name | Guanylate kinase | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000014775 | ||||||||||||
| Encoded Proteins |
Guanylate kinase
Guanylate kinase
Guanylate kinase
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143774:
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 7:2895658-2905969 | ||||||||||||
| Strand | Reverse strand | ||||||||||||
| Band | |||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Metabolism of nucleotides pathway
Abacavir transport and metabolism pathway
Abacavir metabolism pathway
Metabolism pathway
Synthesis and interconversion of nucleotide di- and triphosphates pathway
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Abacavir metabolism pathway
Synthesis and interconversion of nucleotide di- and triphosphates pathway
Metabolism of nucleotides pathway
Abacavir transport and metabolism pathway
Metabolism pathway
Synthesis and interconversion of nucleotide di- and triphosphates pathway
Metabolism pathway
Abacavir metabolism pathway
Abacavir transport and metabolism pathway
Metabolism of nucleotides pathway
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| KEGG |
Purine metabolism pathway
Purine metabolism pathway
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| INOH |
Purine nucleotides nucleosides metabolism pathway
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| PID NCI | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | G8JKX7 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 281217 | ||||||||||||
| UniGene | Bt.4287 | ||||||||||||
| RefSeq | NM_001159412 XM_005208395 NM_001159413 NM_174078 XM_005208398 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | BC102478 DAAA02019006 X67029 | ||||||||||||
| GenPept | AAI02479 CAA47423 | ||||||||||||
| RNA Seq Atlas | 281217 | ||||||||||||