Version 5.4
Bos taurus Protein: GCG
Summary
InnateDB Protein IDBP-693639.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GCG
Protein Name GlucagonGlicentinGlicentin-related polypeptideOxyntomodulinGlucagonGlucagon-like peptide 1Glucagon-like peptide 1(7-37)Glucagon-like peptide 1(7-36)Glucagon-like peptide 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000054709
InnateDB Gene IDBG-641235 (GCG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0010737 protein kinase A signaling
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0032092 positive regulation of protein binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0043066 negative regulation of apoptotic process
GO:0045722 positive regulation of gluconeogenesis
GO:0045860 positive regulation of protein kinase activity
GO:0050796 regulation of insulin secretion
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090280 positive regulation of calcium ion import
GO:1900118 negative regulation of execution phase of apoptosis
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000532 Glucagon/GIP/secretin/VIP
PFAM PF00123
PRINTS PR00275
PIRSF
SMART SM00070
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3MYS1
UniProt Splice Variant
Entrez Gene 280802
UniGene Bt.410
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02004416
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca