InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GCAT

Summary

InnateDB Protein

IDBP-693875.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GCAT

Protein Name

2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000011095

InnateDB Gene

IDBG-641495 (GCAT)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion {ECO:0000269PubMed:8307963}. Nucleus {ECO:0000250}. Note=Translocates to the nucleus upon cold and osmotic stress. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008890	glycine C-acetyltransferase activity
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0019518	L-threonine catabolic process to glycine

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000192 Aminotransferase class V domain
IPR004839 Aminotransferase, class I/classII
IPR011282 2-amino-3-ketobutyrate coenzyme A ligase
IPR015424 Pyridoxal phosphate-dependent transferase

PFAM

PF00266
PF00155

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q0P5L8

PhosphoSite