Version 5.4
Bos taurus Protein: FCN2
Summary
InnateDB Protein IDBP-693977.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCN2
Protein Name Ficolin-2
Synonyms FCN2; FCNB;
Species Bos taurus
Ensembl Protein ENSBTAP00000054518
InnateDB Gene IDBG-641596 (FCN2)
Protein Structure
UniProt Annotation
Function May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001867 complement activation, lectin pathway
GO:0002376 immune system process
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
GO:0005581 collagen trimer
Protein Structure and Domains
PDB ID
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
IPR008160 Collagen triple helix repeat
PFAM PF00147
PF01391
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5I2E5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 497016
UniGene Bt.32312
RefSeq NP_001010996
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY860499
GenPept AAW52550

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca