Version 5.4
Bos taurus Protein: UGDH
Summary
InnateDB Protein IDBP-694151.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UGDH
Protein Name UDP-glucose 6-dehydrogenase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000019302
InnateDB Gene IDBG-641753 (UGDH)
Protein Structure
UniProt Annotation
Function Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003979 UDP-glucose 6-dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding
Biological Process
GO:0001702 gastrulation with mouth forming second
GO:0006065 UDP-glucuronate biosynthetic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation
IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal
IPR017476 UDP-glucose/GDP-mannose dehydrogenase
PFAM PF03721
PF00984
PF03720
PRINTS
PIRSF PIRSF000124
SMART SM00984
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P12378
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281564
UniGene Bt.5538
RefSeq NP_776636
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF095792 BC150068
GenPept AAC64183 AAI50069

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca