InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GH1

Summary

InnateDB Protein

IDBP-694168.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GH1

Protein Name

Somatotropin

Synonyms

GH;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022885

InnateDB Gene

IDBG-641755 (GH1)

Protein Structure

UniProt Annotation

Function

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 72 interaction(s) predicted by orthology.

Predicted by orthology
Total	72 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005131	growth hormone receptor binding
GO:0005179	hormone activity
GO:0046872	metal ion binding

Biological Process

GO:0032094	response to food
GO:0032869	cellular response to insulin stimulus
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway
GO:0040018	positive regulation of multicellular organism growth

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005802	trans-Golgi network
GO:0005886	plasma membrane
GO:0030141	secretory granule