Version 5.4
Bos taurus Protein: FZD4
Summary
InnateDB Protein IDBP-694288.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FZD4
Protein Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000053606
InnateDB Gene IDBG-641882 (FZD4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
GO:0019955 cytokine binding
GO:0030165 PDZ domain binding
GO:0031625 ubiquitin protein ligase binding
GO:0042803 protein homodimerization activity
GO:0042813 Wnt-activated receptor activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0001553 luteinization
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0007166 cell surface receptor signaling pathway
GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway
GO:0007275 multicellular organismal development
GO:0007605 sensory perception of sound
GO:0010812 negative regulation of cell-substrate adhesion
GO:0016055 Wnt signaling pathway
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031987 locomotion involved in locomotory behavior
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035426 extracellular matrix-cell signaling
GO:0042701 progesterone secretion
GO:0043507 positive regulation of JUN kinase activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060070 canonical Wnt signaling pathway
GO:0061299 retina vasculature morphogenesis in camera-type eye
GO:0061301 cerebellum vasculature morphogenesis
GO:0061304 retinal blood vessel morphogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000539 Frizzled protein
IPR017981 GPCR, family 2-like
IPR020067 Frizzled domain
PFAM PF01534
PF01392
PRINTS PR00489
PIRSF
SMART SM00063
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q1MW19
UniProt Splice Variant
Entrez Gene 445416
UniGene Bt.76547
RefSeq NP_001193198
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB257753 DAAA02062527
GenPept BAE93504

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca