Version 5.4
Bos taurus Protein: POLG2
Summary
InnateDB Protein IDBP-694289.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLG2
Protein Name DNA polymerase subunit gamma-2, mitochondrial
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000024509
InnateDB Gene IDBG-641880 (POLG2)
Protein Structure
UniProt Annotation
Function Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0016779 nucleotidyltransferase activity
GO:0042802 identical protein binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
Cellular Component
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR004154 Anticodon-binding
PFAM PF03129
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0VC30
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 505152
UniGene Bt.52381
RefSeq NP_001068659
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120380
GenPept AAI20381

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca