InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NLRP6

Summary

InnateDB Protein

IDBP-694373.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NLRP6

Protein Name

NLR family, pyrin domain containing 6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001428

InnateDB Gene

IDBG-641962 (NLRP6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005524	ATP binding

Biological Process

GO:0006952	defense response
GO:0009617	response to bacterium
GO:0034122	negative regulation of toll-like receptor signaling pathway
GO:0042060	wound healing
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043409	negative regulation of MAPK cascade
GO:0050727	regulation of inflammatory response
GO:0050777	negative regulation of immune response

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR004020 DAPIN domain
IPR007111 NACHT nucleoside triphosphatase
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02758

PRINTS

PIRSF

SMART

SM00368

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite