InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HEPACAM

Summary

InnateDB Protein

IDBP-695128.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HEPACAM

Protein Name

Hepatocyte cell adhesion molecule

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000030280

InnateDB Gene

IDBG-642655 (HEPACAM)

Protein Structure

UniProt Annotation

Function

Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation (By similarity). {ECO:0000250UniProtKB:Q14CZ8}.

Subcellular Localization

Cytoplasm. Membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250UniProtKB:Q14CZ8}. Note=Colocalizes with CDH1. {ECO:0000250UniProtKB:Q14CZ8}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007049	cell cycle
GO:0007050	cell cycle arrest
GO:0007155	cell adhesion
GO:0034613	cellular protein localization
GO:0040008	regulation of growth

Cellular Component

GO:0005737	cytoplasm
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon

Protein Structure and Domains

PDB ID

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A4FUY1