Version 5.4
Bos taurus Protein: HSPE1
Summary
InnateDB Protein IDBP-695451.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPE1
Protein Name 10 kDa heat shock protein, mitochondrial
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000016712
InnateDB Gene IDBG-642941 (HSPE1)
Protein Structure
UniProt Annotation
Function Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
Subcellular Localization Mitochondrion matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0044822 poly(A) RNA binding
GO:0051087 chaperone binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0006457 protein folding
GO:0006950 response to stress
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR011032 GroES (chaperonin 10)-like
IPR020818 Chaperonin Cpn10
PFAM PF00166
PRINTS PR00297
PIRSF
SMART SM00883
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P61603
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281833
UniGene Bt.62396
RefSeq NP_776771
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102684 X69556
GenPept AAI02685 CAA49288

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca