Version 5.4
Bos taurus Gene: HSPE1
Summary
InnateDB Gene IDBG-642941.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPE1
Gene Name 10 kDa heat shock protein, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012589
Encoded Proteins
IDBP-695451
10 kDa heat shock protein, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115541:
This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:86449525-86451564
Strand Forward strand
Band
Transcripts
ENSBTAT00000016712 ENSBTAP00000016712
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0044822 poly(A) RNA binding
GO:0051087 chaperone binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0006457 protein folding
GO:0006950 response to stress
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000115541
View Gene Order
ENSMUSG00000073676
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt P61603
TrEMBL
UniProt Splice Variant
Entrez Gene 281833
UniGene Bt.62396
RefSeq NM_174346
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102684 X69556
GenPept AAI02685 CAA49288
RNA Seq Atlas 281833

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca