Version 5.4
Bos taurus Protein: KEAP1
Summary
InnateDB Protein IDBP-695840.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KEAP1
Protein Name kelch-like ECH-associated protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000004604
InnateDB Gene IDBG-643288 (KEAP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 73 interaction(s) predicted by orthology.
Predicted by orthology
Total 73 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006355 regulation of transcription, DNA-templated
GO:0010499 proteasomal ubiquitin-independent protein catabolic process
GO:0045604 regulation of epidermal cell differentiation
GO:0071353 cellular response to interleukin-4
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005815 microtubule organizing center
GO:0030496 midbody
GO:0031463 Cul3-RING ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR006652 Kelch repeat type 1
IPR011333 BTB/POZ fold
IPR011498 Kelch repeat type 2
IPR011705 BTB/Kelch-associated
IPR013069 BTB/POZ
IPR017096 Kelch-like protein, gigaxonin type
PFAM PF01344
PF07646
PF07707
PF00651
PRINTS
PIRSF PIRSF037037
SMART SM00225
SM00612
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0V8M8
UniProt Splice Variant
Entrez Gene 532791
UniGene Bt.2184
RefSeq NP_001094612
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151545 BT026190 DAAA02019465
GenPept AAI51546 ABG67029

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca