InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NRP2

Summary

InnateDB Protein

IDBP-695953.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NRP2

Protein Name

neuropilin 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015885

InnateDB Gene

IDBG-643390 (NRP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005021	vascular endothelial growth factor-activated receptor activity
GO:0005515	protein binding
GO:0017154	semaphorin receptor activity
GO:0046872	metal ion binding

Biological Process

GO:0001525	angiogenesis
GO:0001755	neural crest cell migration
GO:0001764	neuron migration
GO:0007155	cell adhesion
GO:0007411	axon guidance
GO:0007507	heart development
GO:0021675	nerve development
GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO:0038084	vascular endothelial growth factor signaling pathway
GO:0048846	axon extension involved in axon guidance
GO:0050919	negative chemotaxis
GO:0061549	sympathetic ganglion development
GO:0097490	sympathetic neuron projection extension
GO:0097491	sympathetic neuron projection guidance
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance

Cellular Component

GO:0016020	membrane
GO:0030424	axon

Protein Structure and Domains

PDB ID

InterPro

IPR000421 Coagulation factor 5/8 C-terminal type domain
IPR000859 CUB domain
IPR000998 MAM domain
IPR008979 Galactose-binding domain-like
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR014648 Neuropilin
IPR022579 Neuropilin-1, C-terminal

PFAM

PF00754
PF00431
PF00629
PF11980

PRINTS

PR00020

PIRSF

PIRSF036960

SMART

SM00231
SM00042
SM00137

TIGRFAMs

Post-translational Modifications

Modification

Cross-References