Version 5.4
Bos taurus Protein: KCNJ2
Summary
InnateDB Protein IDBP-696128.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNJ2
Protein Name Inward rectifier potassium channel 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000010914
InnateDB Gene IDBG-643567 (KCNJ2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005244 voltage-gated ion channel activity
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0042802 identical protein binding
GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0010107 potassium ion import
GO:0014861 regulation of skeletal muscle contraction via regulation of action potential
GO:0015693 magnesium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0051289 protein homotetramerization
GO:0055119 relaxation of cardiac muscle
GO:0060306 regulation of membrane repolarization
GO:0071805 potassium ion transmembrane transport
GO:0086001 cardiac muscle cell action potential
GO:0086002 cardiac muscle cell action potential involved in contraction
GO:0086011 membrane repolarization during action potential
GO:0086013 membrane repolarization during cardiac muscle cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0090076 relaxation of skeletal muscle
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031224 intrinsic component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003271 Potassium channel, inwardly rectifying, Kir2.1
IPR013673 Potassium channel, inwardly rectifying, Kir, N-terminal
IPR014756 Immunoglobulin E-set
IPR016449 Potassium channel, inwardly rectifying, Kir
PFAM PF08466
PF01007
PRINTS PR01324
PR01320
PIRSF PIRSF005465
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O19182
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281883
UniGene Bt.126
RefSeq NP_776798
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF020792 AY052548 U95369
GenPept AAB71888 AAC48735 AAL05937

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca