Bos taurus Protein: GALNT1 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-696207.2 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | GALNT1 | ||||||||||||
Protein Name | Polypeptide N-acetylgalactosaminyltransferase 1Polypeptide N-acetylgalactosaminyltransferase 1 soluble form | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Protein | ENSBTAP00000014882 | ||||||||||||
InnateDB Gene | IDBG-643633 (GALNT1) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7. {ECO:0000269PubMed:3082881, ECO:0000269PubMed:7685345}. | ||||||||||||
Subcellular Localization | Polypeptide N- acetylgalactosaminyltransferase 1: Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.Polypeptide N- acetylgalactosaminyltransferase 1 soluble form: Secreted {ECO:0000250}. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | Colostrum contains a soluble form. {ECO:0000269PubMed:3082881}. | ||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR000772
Ricin B lectin domain IPR001173 Glycosyltransferase 2-like IPR029044 Nucleotide-diphospho-sugar transferases |
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PFAM |
PF00652
PF14200 PF00535 |
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PRINTS | |||||||||||||
PIRSF | |||||||||||||
SMART |
SM00458
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TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q07537 | ||||||||||||
PhosphoSite | PhosphoSite- | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 282241 | ||||||||||||
UniGene | Bt.65693 | ||||||||||||
RefSeq | NP_803485 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | L07780 L17437 | ||||||||||||
GenPept | AAA30532 AAA68489 | ||||||||||||