InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ABCA12

Summary

InnateDB Protein

IDBP-696216.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCA12

Protein Name

ATP-binding cassette, sub-family A (ABC1), member 12

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000004518

InnateDB Gene

IDBG-643637 (ABCA12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005102	receptor binding
GO:0005319	lipid transporter activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0034191	apolipoprotein A-I receptor binding

Biological Process

GO:0006200	ATP catabolic process
GO:0008152	metabolic process
GO:0010875	positive regulation of cholesterol efflux
GO:0030216	keratinocyte differentiation
GO:0031424	keratinization
GO:0032940	secretion by cell
GO:0033700	phospholipid efflux
GO:0035627	ceramide transport
GO:0043129	surfactant homeostasis
GO:0045055	regulated secretory pathway
GO:0048286	lung alveolus development
GO:0055088	lipid homeostasis
GO:0061436	establishment of skin barrier
GO:0072659	protein localization to plasma membrane
GO:2000010	positive regulation of protein localization to cell surface

Cellular Component

GO:0005737	cytoplasm
GO:0005743	mitochondrial inner membrane
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0097209	epidermal lamellar body

Protein Structure and Domains

PDB ID

InterPro

IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00005

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G5E556

UniProt Splice Variant

Entrez Gene

523479

UniGene

Bt.60068

RefSeq

NP_001178223

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02005862 DAAA02005863 DAAA02005864

GenPept