Version 5.4
Bos taurus Protein: PARP10
Summary
InnateDB Protein IDBP-696243.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PARP10
Protein Name poly (ADP-ribose) polymerase family, member 10
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000012765
InnateDB Gene IDBG-643666 (PARP10)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0070530 K63-linked polyubiquitin binding
Biological Process
GO:0006471 protein ADP-ribosylation
GO:0010629 negative regulation of gene expression
GO:0010847 regulation of chromatin assembly
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0033159 negative regulation of protein import into nucleus, translocation
GO:0045071 negative regulation of viral genome replication
GO:0048147 negative regulation of fibroblast proliferation
GO:0070212 protein poly-ADP-ribosylation
GO:0070213 protein auto-ADP-ribosylation
GO:1900045 negative regulation of protein K63-linked ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Protein Structure and Domains
PDB ID
InterPro IPR003903 Ubiquitin interacting motif
IPR012317 Poly(ADP-ribose) polymerase, catalytic domain
PFAM PF02809
PF00644
PRINTS
PIRSF
SMART SM00726
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MRP9
UniProt Splice Variant
Entrez Gene 510991
UniGene
RefSeq XP_002692594
HUGO HGNC:25895
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02037451
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca