Version 5.4
Bos taurus Gene: PARP10
Summary
InnateDB Gene IDBG-643666.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PARP10
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009677
Encoded Proteins
IDBP-696243
poly (ADP-ribose) polymerase family, member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178685:
Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:2024713-2031386
Strand Forward strand
Band
Transcripts
ENSBTAT00000012765 ENSBTAP00000012765
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0070530 K63-linked polyubiquitin binding
Biological Process
GO:0006471 protein ADP-ribosylation
GO:0010629 negative regulation of gene expression
GO:0010847 regulation of chromatin assembly
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0033159 negative regulation of protein import into nucleus, translocation
GO:0045071 negative regulation of viral genome replication
GO:0048147 negative regulation of fibroblast proliferation
GO:0070212 protein poly-ADP-ribosylation
GO:0070213 protein auto-ADP-ribosylation
GO:1900045 negative regulation of protein K63-linked ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000178685
View Gene Order
ENSMUSG00000063268
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq XM_002692548 XM_588232
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca