Version 5.4
Bos taurus Protein: FKBP2
Summary
InnateDB Protein IDBP-696499.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FKBP2
Protein Name Peptidyl-prolyl cis-trans isomerase FKBP2
Synonyms FKBP-2;
Species Bos taurus
Ensembl Protein ENSBTAP00000018091
InnateDB Gene IDBG-643901 (FKBP2)
Protein Structure
UniProt Annotation
Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005528 FK506 binding
GO:0016853 isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
PFAM PF00254
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q32PA9
PhosphoSite PhosphoSite-
TrEMBL G1K1P8
UniProt Splice Variant
Entrez Gene 538998
UniGene
RefSeq NP_001106727
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC108190 DAAA02063529
GenPept AAI08191

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca