Bos taurus Gene: FKBP2
Summary
InnateDB Gene IDBG-643901.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FKBP2
Gene Name Peptidyl-prolyl cis-trans isomerase FKBP2
Synonyms FKBP-2
Species Bos taurus
Ensembl Gene ENSBTAG00000013606
Encoded Proteins
Peptidyl-prolyl cis-trans isomerase FKBP2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173486:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:43159739-43162644
Strand Forward strand
Band
Transcripts
ENSBTAT00000018091 ENSBTAP00000018091
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005528 FK506 binding
GO:0016853 isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q32PA9
TrEMBL G1K1P8
UniProt Splice Variant
Entrez Gene 538998
UniGene
RefSeq NM_001037481 NM_001113256
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC108190 DAAA02063529
GenPept AAI08191
RNA Seq Atlas 538998