InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ACER1

Summary

InnateDB Protein

IDBP-696583.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACER1

Protein Name

alkaline ceramidase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000010648

InnateDB Gene

IDBG-643977 (ACER1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017040	ceramidase activity
GO:0071633	dihydroceramidase activity

Biological Process

GO:0006665	sphingolipid metabolic process
GO:0006672	ceramide metabolic process
GO:0008544	epidermis development
GO:0010446	response to alkalinity
GO:0019216	regulation of lipid metabolic process
GO:0030148	sphingolipid biosynthetic process
GO:0030154	cell differentiation
GO:0030216	keratinocyte differentiation
GO:0046512	sphingosine biosynthetic process
GO:0046514	ceramide catabolic process
GO:0071277	cellular response to calcium ion

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR008901 Ceramidase

PFAM

PF05875

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MGH9

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:18356

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02019568

GenPept