Version 5.4
Bos taurus Protein: ADCYAP1
Summary
InnateDB Protein IDBP-696753.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADCYAP1
Protein Name pituitary adenylate cyclase-activating polypeptide
Synonyms PACAP;
Species Bos taurus
Ensembl Protein ENSBTAP00000027516
InnateDB Gene IDBG-644139 (ADCYAP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0005102 receptor binding
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0016521 pituitary adenylate cyclase activating polypeptide activity
GO:0051428 peptide hormone receptor binding
Biological Process
GO:0007218 neuropeptide signaling pathway
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0010579 positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0010628 positive regulation of gene expression
GO:0019933 cAMP-mediated signaling
GO:0031175 neuron projection development
GO:0032854 positive regulation of Rap GTPase activity
GO:0032880 regulation of protein localization
GO:0045786 negative regulation of cell cycle
GO:0045860 positive regulation of protein kinase activity
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0070374 positive regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000532 Glucagon/GIP/secretin/VIP
PFAM PF00123
PRINTS PR00275
PIRSF
SMART SM00070
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A4FV02
UniProt Splice Variant
Entrez Gene 615187
UniGene Bt.56289
RefSeq NP_001040020
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123523 DAAA02056663
GenPept AAI23524

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca