Version 5.4
Bos taurus Protein: TGIF1
Summary
InnateDB Protein IDBP-696827.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TGIF1
Protein Name TGFB-induced factor homeobox 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000039058
InnateDB Gene IDBG-644209 (TGIF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001843 neural tube closure
GO:0006355 regulation of transcription, DNA-templated
GO:0007368 determination of left/right symmetry
GO:0008285 negative regulation of cell proliferation
GO:0009953 dorsal/ventral pattern formation
GO:0010470 regulation of gastrulation
GO:0038092 nodal signaling pathway
GO:0045666 positive regulation of neuron differentiation
GO:0048146 positive regulation of fibroblast proliferation
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0060041 retina development in camera-type eye
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR008422 Homeobox KN domain
IPR009057 Homeodomain-like
PFAM PF00046
PF05920
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3MIB9
UniProt Splice Variant
Entrez Gene 510050
UniGene Bt.49627
RefSeq NP_001121971
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103302 DAAA02056733
GenPept AAI03303

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca