Version 5.4
Bos taurus Protein: SULF1
Summary
InnateDB Protein IDBP-697341.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SULF1
Protein Name sulfatase 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000037103
InnateDB Gene IDBG-644683 (SULF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004065 arylsulfatase activity
GO:0005509 calcium ion binding
GO:0008449 N-acetylglucosamine-6-sulfatase activity
GO:0008484 sulfuric ester hydrolase activity
Biological Process
GO:0001502 cartilage condensation
GO:0001822 kidney development
GO:0001937 negative regulation of endothelial cell proliferation
GO:0002063 chondrocyte development
GO:0003094 glomerular filtration
GO:0007155 cell adhesion
GO:0008152 metabolic process
GO:0010575 positive regulation vascular endothelial growth factor production
GO:0014846 esophagus smooth muscle contraction
GO:0016525 negative regulation of angiogenesis
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030201 heparan sulfate proteoglycan metabolic process
GO:0030336 negative regulation of cell migration
GO:0030513 positive regulation of BMP signaling pathway
GO:0032836 glomerular basement membrane development
GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway
GO:0036022 limb joint morphogenesis
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048706 embryonic skeletal system development
GO:0051216 cartilage development
GO:0060348 bone development
GO:0060384 innervation
GO:0060686 negative regulation of prostatic bud formation
Cellular Component
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID
InterPro IPR000917 Sulfatase
IPR014615 Extracellular sulfatase
IPR017850 Alkaline-phosphatase-like, core domain
IPR024609 Extracellular sulfatase, C-terminal
PFAM PF00884
PF12548
PRINTS
PIRSF PIRSF036665
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BGL6
UniProt Splice Variant
Entrez Gene
UniGene Bt.112263
RefSeq
HUGO HGNC:20391
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02038770 DAAA02038771 DAAA02038772
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca