InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MBD2

Summary

InnateDB Protein

IDBP-697398.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MBD2

Protein Name

methyl-CpG binding domain protein 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000048789

InnateDB Gene

IDBG-644736 (MBD2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0008327	methyl-CpG binding
GO:0019904	protein domain specific binding
GO:0031492	nucleosomal DNA binding
GO:0035197	siRNA binding
GO:0070742	C2H2 zinc finger domain binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0030177	positive regulation of Wnt signaling pathway
GO:0042127	regulation of cell proliferation
GO:0042711	maternal behavior
GO:0043044	ATP-dependent chromatin remodeling
GO:0043623	cellular protein complex assembly

Cellular Component

GO:0000118	histone deacetylase complex
GO:0000785	chromatin
GO:0000790	nuclear chromatin
GO:0000792	heterochromatin
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0043234	protein complex