InnateDB Protein
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IDBP-697437.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BT.91190
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Protein Name
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transcription factor 7-like 2
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Synonyms
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TCF7L2;
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000030974
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InnateDB Gene
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IDBG-644769 (BT.91190)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 86 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
86 [view]
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Molecular Function |
Accession |
GO Term |
GO:0000978
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RNA polymerase II core promoter proximal region sequence-specific DNA binding
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GO:0001011
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sequence-specific DNA binding RNA polymerase recruiting transcription factor activity
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GO:0001077
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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0001087
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TFIIB-class binding transcription factor activity
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GO:0001093
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TFIIB-class transcription factor binding
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GO:0003677
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DNA binding
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GO:0003714
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transcription corepressor activity
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GO:0005515
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protein binding
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GO:0046982
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protein heterodimerization activity
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GO:0046983
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protein dimerization activity
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GO:0070888
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E-box binding
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Biological Process |
GO:0000122
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negative regulation of transcription from RNA polymerase II promoter
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GO:0006352
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DNA-templated transcription, initiation
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0006367
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transcription initiation from RNA polymerase II promoter
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GO:0045666
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positive regulation of neuron differentiation
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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GO:0065004
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protein-DNA complex assembly
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Cellular Component |
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PDB ID |
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InterPro |
IPR011598
Myc-type, basic helix-loop-helix (bHLH) domain
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PFAM |
PF00010
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PRINTS |
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PIRSF |
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SMART |
SM00353
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
A6QPK5
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UniProt Splice Variant |
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Entrez Gene |
534935
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UniGene |
Bt.91190
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RefSeq |
XP_005224275
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AB447354
BC149366
DAAA02057094
DAAA02057095
DAAA02057096
DAAA02057097
DAAA02057098
DAAA02057099
DAAA02057100
DAAA02057101
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GenPept |
AAI49367
BAH10707
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