Bos taurus Protein: BT.91190
Summary
InnateDB Protein IDBP-697437.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.91190
Protein Name transcription factor 7-like 2
Synonyms TCF7L2;
Species Bos taurus
Ensembl Protein ENSBTAP00000030974
InnateDB Gene IDBG-644769 (BT.91190)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 86 interaction(s) predicted by orthology.
Predicted by orthology
Total 86 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001011 sequence-specific DNA binding RNA polymerase recruiting transcription factor activity
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001087 TFIIB-class binding transcription factor activity
GO:0001093 TFIIB-class transcription factor binding
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
GO:0070888 E-box binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0065004 protein-DNA complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF00010
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A6QPK5
UniProt Splice Variant
Entrez Gene 534935
UniGene Bt.91190
RefSeq XP_005224275
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB447354 BC149366 DAAA02057094 DAAA02057095 DAAA02057096 DAAA02057097 DAAA02057098 DAAA02057099 DAAA02057100 DAAA02057101
GenPept AAI49367 BAH10707