InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ATP8B1

Summary

InnateDB Protein

IDBP-697490.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP8B1

Protein Name

ATPase, aminophospholipid transporter, class I, type 8B, member 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007542

InnateDB Gene

IDBG-644820 (ATP8B1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding
GO:1901612	cardiolipin binding

Biological Process

GO:0006812	cation transport
GO:0006855	drug transmembrane transport
GO:0007605	sensory perception of sound
GO:0008206	bile acid metabolic process
GO:0015914	phospholipid transport
GO:0021650	vestibulocochlear nerve formation
GO:0032534	regulation of microvillus assembly
GO:0045332	phospholipid translocation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0060119	inner ear receptor cell development

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0032420	stereocilium

Protein Structure and Domains

PDB ID

InterPro

IPR001757 Cation-transporting P-type ATPase
IPR006539 Cation-transporting P-type ATPase, subfamily IV
IPR008250 P-type ATPase, A domain
IPR023214 HAD-like domain
IPR023299 P-type ATPase, cytoplasmic domain N

PFAM

PF00122
PF00702
PF08282
PF13419

PRINTS

PR00119
PR00120

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite