InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC12A2

Summary

InnateDB Protein

IDBP-697537.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC12A2

Protein Name

solute carrier family 12 member 2

Synonyms

bsc2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000012701

InnateDB Gene

IDBG-644856 (SLC12A2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0008519	ammonium transmembrane transporter activity
GO:0015377	cation:chloride symporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0015696	ammonium transport
GO:0030321	transepithelial chloride transport
GO:0035264	multicellular organism growth
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
GO:0055085	transmembrane transport
GO:0060444	branching involved in mammary gland duct morphogenesis
GO:0060763	mammary duct terminal end bud growth
GO:0070634	transepithelial ammonium transport
GO:0072488	ammonium transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002443 Na/K/Cl co-transporter
IPR002444 Na/K/Cl co-transporter 1
IPR004841 Amino acid permease/ SLC12A domain
IPR004842 Na/K/Cl co-transporter superfamily
IPR013612 Amino acid permease, N-terminal

PFAM

PF00324
PF08403

PRINTS

PR01207
PR01208

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite