Version 5.4
Bos taurus Protein: ANGPT1
Summary
InnateDB Protein IDBP-697615.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANGPT1
Protein Name angiopoietin-1 precursor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018675
InnateDB Gene IDBG-644947 (ANGPT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0030971 receptor tyrosine kinase binding
Biological Process
GO:0001525 angiogenesis
GO:0001701 in utero embryonic development
GO:0002040 sprouting angiogenesis
GO:0002092 positive regulation of receptor internalization
GO:0007162 negative regulation of cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity
GO:0010595 positive regulation of endothelial cell migration
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014842 regulation of satellite cell proliferation
GO:0030097 hemopoiesis
GO:0030210 heparin biosynthetic process
GO:0031398 positive regulation of protein ubiquitination
GO:0031589 cell-substrate adhesion
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034394 protein localization to cell surface
GO:0043066 negative regulation of apoptotic process
GO:0043116 negative regulation of vascular permeability
GO:0043524 negative regulation of neuron apoptotic process
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045785 positive regulation of cell adhesion
GO:0048014 Tie signaling pathway
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918 positive chemotaxis
GO:0051897 positive regulation of protein kinase B signaling
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0072012 glomerulus vasculature development
GO:2000352 negative regulation of endothelial cell apoptotic process
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
PFAM PF00147
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G8JKX3
UniProt Splice Variant
Entrez Gene 282140
UniGene
RefSeq NP_001070265
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02039227 DAAA02039228 DAAA02039229 DAAA02039230 DAAA02039231
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca