InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KCNQ1

Summary

InnateDB Protein

IDBP-697878.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNQ1

Protein Name

potassium voltage-gated channel, KQT-like subfamily, member 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000014583

InnateDB Gene

IDBG-645190 (KCNQ1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005267	potassium channel activity
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0008157	protein phosphatase 1 binding
GO:0034236	protein kinase A catalytic subunit binding
GO:0034237	protein kinase A regulatory subunit binding
GO:0044325	ion channel binding
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
GO:0097110	scaffold protein binding
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

Biological Process

GO:0006349	regulation of gene expression by genetic imprinting
GO:0006810	transport
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0016458	gene silencing
GO:0035690	cellular response to drug
GO:0055085	transmembrane transport
GO:0060048	cardiac muscle contraction
GO:0060306	regulation of membrane repolarization
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
GO:0071320	cellular response to cAMP
GO:0071435	potassium ion export
GO:0071805	potassium ion transmembrane transport
GO:0072358	cardiovascular system development
GO:0086005	ventricular cardiac muscle cell action potential
GO:0086011	membrane repolarization during action potential
GO:0086014	atrial cardiac muscle cell action potential
GO:0086091	regulation of heart rate by cardiac conduction
GO:1901381	positive regulation of potassium ion transmembrane transport

Cellular Component

GO:0005764	lysosome
GO:0005769	early endosome
GO:0005770	late endosome
GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003091 Potassium channel
IPR003937 Potassium channel, voltage dependent, KCNQ
IPR005821 Ion transport domain
IPR005827 Potassium channel, voltage dependent, KCNQ1
IPR013099 Two pore domain potassium channel domain

PFAM

PF00520
PF07885

PRINTS

PR00169
PR01459
PR01460

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite