InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RGS14

Summary

InnateDB Protein

IDBP-697939.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RGS14

Protein Name

regulator of G-protein signaling 14

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000011200

InnateDB Gene

IDBG-645245 (RGS14)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005057	receptor signaling protein activity
GO:0005092	GDP-dissociation inhibitor activity
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0030695	GTPase regulator activity
GO:0032794	GTPase activating protein binding

Biological Process

GO:0006913	nucleocytoplasmic transport
GO:0007051	spindle organization
GO:0007059	chromosome segregation
GO:0007067	mitotic nuclear division
GO:0007165	signal transduction
GO:0007612	learning
GO:0007616	long-term memory
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
GO:0010070	zygote asymmetric cell division
GO:0031914	negative regulation of synaptic plasticity
GO:0035556	intracellular signal transduction
GO:0038032	termination of G-protein coupled receptor signaling pathway
GO:0043407	negative regulation of MAP kinase activity
GO:0043620	regulation of DNA-dependent transcription in response to stress
GO:0051301	cell division
GO:0060291	long-term synaptic potentiation

Cellular Component

GO:0005634	nucleus
GO:0005813	centrosome
GO:0005819	spindle
GO:0014069	postsynaptic density
GO:0016604	nuclear body
GO:0030425	dendrite
GO:0043197	dendritic spine

Protein Structure and Domains

PDB ID

InterPro

IPR000342 Regulator of G protein signalling domain
IPR003109 GoLoco motif
IPR003116 Raf-like Ras-binding
IPR016137 Regulator of G protein signalling superfamily
IPR029071 Ubiquitin-related domain

PFAM

PF00615
PF02188
PF02196

PRINTS

PR01301

PIRSF

SMART

SM00390
SM00455
SM00315

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt