InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TNNT3

Summary

InnateDB Protein

IDBP-697962.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNNT3

Protein Name

Troponin T, fast skeletal muscle

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000054396

InnateDB Gene

IDBG-645251 (TNNT3)

Protein Structure

UniProt Annotation

Function

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005523	tropomyosin binding
GO:0030172	troponin C binding
GO:0030899	calcium-dependent ATPase activity
GO:0031013	troponin I binding
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0003009	skeletal muscle contraction
GO:0006200	ATP catabolic process
GO:0006937	regulation of muscle contraction
GO:0006942	regulation of striated muscle contraction
GO:0043462	regulation of ATPase activity

Cellular Component

GO:0005861

troponin complex

Protein Structure and Domains

PDB ID

InterPro

IPR001978 Troponin

PFAM

PF00992

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8MKI3

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

282096

UniGene

Bt.11215

RefSeq

XP_005227336

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB085593

GenPept

BAB92976