InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PKM2

Summary

InnateDB Protein

IDBP-698290.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PKM2

Protein Name

Pyruvate kinase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000044619

InnateDB Gene

IDBG-645572 (PKM2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 87 interaction(s) predicted by orthology.

Predicted by orthology
Total	87 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0003824	catalytic activity
GO:0004743	pyruvate kinase activity
GO:0005515	protein binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0023026	MHC class II protein complex binding
GO:0030955	potassium ion binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006096	glycolytic process
GO:0012501	programmed cell death
GO:0016310	phosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0005929	cilium
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001697 Pyruvate kinase
IPR011037 Pyruvate kinase-like, insert domain
IPR015793 Pyruvate kinase, barrel
IPR015795 Pyruvate kinase, C-terminal
IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain

PFAM

PF00224
PF02887

PRINTS

PR01050

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite