Version 5.4
Bos taurus Protein: PCSK4
Summary
InnateDB Protein IDBP-698369.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCSK4
Protein Name proprotein convertase subtilisin/kexin type 4
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002975
InnateDB Gene IDBG-645644 (PCSK4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0007339 binding of sperm to zona pellucida
GO:0007340 acrosome reaction
GO:0009566 fertilization
GO:0048240 sperm capacitation
Cellular Component
GO:0002080 acrosomal membrane
Protein Structure and Domains
PDB ID
InterPro IPR000209 Peptidase S8/S53 domain
IPR002884 Proprotein convertase, P
IPR008979 Galactose-binding domain-like
IPR009020 Proteinase inhibitor, propeptide
IPR015500 Peptidase S8, subtilisin-related
PFAM PF00082
PF01483
PRINTS PR00723
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5E527
UniProt Splice Variant
Entrez Gene
UniGene Bt.77029
RefSeq
HUGO HGNC:8746
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020264 DAAA02020265
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca