Version 5.4
Bos taurus Protein: METTL3
Summary
InnateDB Protein IDBP-698757.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol METTL3
Protein Name N6-adenosine-methyltransferase 70 kDa subunit
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020151
InnateDB Gene IDBG-645993 (METTL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
Biological Process
GO:0001510 RNA methylation
GO:0006139 nucleobase-containing compound metabolic process
GO:0006397 mRNA processing
GO:0007623 circadian rhythm
GO:0019827 stem cell maintenance
GO:0061157 mRNA destabilization
GO:0080009 mRNA methylation
Cellular Component
GO:0005634 nucleus
GO:0016607 nuclear speck
GO:0036396 MIS complex
Protein Structure and Domains
PDB ID
InterPro IPR007757 MT-A70-like
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF05063
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MX80
UniProt Splice Variant
Entrez Gene 540339
UniGene Bt.13303
RefSeq NP_001095708
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02028311
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca