Version 5.4
Bos taurus Protein: SIL1
Summary
InnateDB Protein IDBP-698768.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIL1
Protein Name Nucleotide exchange factor SIL1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000045075
InnateDB Gene IDBG-646004 (SIL1)
Protein Structure
UniProt Annotation
Function Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5 (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum lumen {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0006810 transport
GO:0015031 protein transport
Cellular Component
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID
InterPro IPR016024 Armadillo-type fold
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q32KV6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 520650
UniGene Bt.47755
RefSeq NP_001069276
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109907
GenPept AAI09908

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca