Version 5.4
Bos taurus Gene: SIL1
Summary
InnateDB Gene IDBG-646004.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIL1
Gene Name Nucleotide exchange factor SIL1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000033747
Encoded Proteins
IDBP-698768
Nucleotide exchange factor SIL1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120725:
This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:51888630-52144488
Strand Reverse strand
Band
Transcripts
ENSBTAT00000047926 ENSBTAP00000045075
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0006810 transport
GO:0015031 protein transport
Cellular Component
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000120725
View Gene Order
ENSMUSG00000024357
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q32KV6
TrEMBL
UniProt Splice Variant
Entrez Gene 520650
UniGene Bt.20070 Bt.47755
RefSeq NM_001075808 XM_005199058 XM_005209438 XM_005209439 XM_005209440 XM_005209441 XM_005209442 XM_005209443 XM_005209444
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109907
GenPept AAI09908
RNA Seq Atlas 101909383 520650

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca