InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC12A6

Summary

InnateDB Protein

IDBP-698881.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC12A6

Protein Name

solute carrier family 12 (potassium/chloride transporters), member 6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021604

InnateDB Gene

IDBG-646104 (SLC12A6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0015079	potassium ion transmembrane transporter activity
GO:0015377	cation:chloride symporter activity
GO:0015379	potassium:chloride symporter activity
GO:0019901	protein kinase binding
GO:0035827	rubidium ion transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0010107	potassium ion import
GO:0035826	rubidium ion transport
GO:0055085	transmembrane transport
GO:0071476	cellular hypotonic response
GO:0071477	cellular hypotonic salinity response
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000076 K-Cl co-transporter
IPR004841 Amino acid permease/ SLC12A domain
IPR004842 Na/K/Cl co-transporter superfamily
IPR018491 K/Cl co-transporter, type 1/type 3

PFAM

PF00324
PF03522

PRINTS

PR01081

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite