Version 5.4
Bos taurus Protein: NDFIP1
Summary
InnateDB Protein IDBP-698909.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDFIP1
Protein Name Nedd4 family interacting protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000054255
InnateDB Gene IDBG-646130 (NDFIP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0050699 WW domain binding
Biological Process
GO:0002761 regulation of myeloid leukocyte differentiation
GO:0002829 negative regulation of type 2 immune response
GO:0006879 cellular iron ion homeostasis
GO:0007165 signal transduction
GO:0010629 negative regulation of gene expression
GO:0031398 positive regulation of protein ubiquitination
GO:0032410 negative regulation of transporter activity
GO:0032713 negative regulation of interleukin-4 production
GO:0042130 negative regulation of T cell proliferation
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045619 regulation of lymphocyte differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0048294 negative regulation of isotype switching to IgE isotypes
GO:0048302 regulation of isotype switching to IgG isotypes
GO:0050728 negative regulation of inflammatory response
GO:0051224 negative regulation of protein transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005938 cell cortex
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR019325 NEDD4/BSD2
PFAM PF10176
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3MXI8
UniProt Splice Variant
Entrez Gene 541196
UniGene
RefSeq XP_002689314
HUGO HGNC:17592
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020452
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca