Version 5.4
Bos taurus Gene: NDFIP1
Summary
InnateDB Gene IDBG-646130.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDFIP1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000047747
Encoded Proteins
IDBP-698909
Nedd4 family interacting protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131507:
The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:55061328-55085013
Strand Forward strand
Band
Transcripts
ENSBTAT00000064420 ENSBTAP00000054255
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0050699 WW domain binding
Biological Process
GO:0002761 regulation of myeloid leukocyte differentiation
GO:0002829 negative regulation of type 2 immune response
GO:0006879 cellular iron ion homeostasis
GO:0007165 signal transduction
GO:0010629 negative regulation of gene expression
GO:0031398 positive regulation of protein ubiquitination
GO:0032410 negative regulation of transporter activity
GO:0032713 negative regulation of interleukin-4 production
GO:0042130 negative regulation of T cell proliferation
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045619 regulation of lymphocyte differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0048294 negative regulation of isotype switching to IgE isotypes
GO:0048302 regulation of isotype switching to IgG isotypes
GO:0050728 negative regulation of inflammatory response
GO:0051224 negative regulation of protein transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005938 cell cortex
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000131507
View Gene Order
ENSMUSG00000024425
View Gene Order
Cross-References
SwissProt
TrEMBL G3MXI8
UniProt Splice Variant
Entrez Gene 541196
UniGene
RefSeq XM_002689268
HUGO HGNC:17592
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020452
GenPept
RNA Seq Atlas 541196
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca