Version 5.4
Bos taurus Protein: GR-A
Summary
InnateDB Protein IDBP-698914.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GR-A
Protein Name Uncharacterized protein
Synonyms GR-A;
Species Bos taurus
Ensembl Protein ENSBTAP00000025941
InnateDB Gene IDBG-646140 (GR-A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 175 interaction(s) predicted by orthology.
Predicted by orthology
Total 175 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004883 glucocorticoid receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006111 regulation of gluconeogenesis
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008211 glucocorticoid metabolic process
GO:0030325 adrenal gland development
GO:0031946 regulation of glucocorticoid biosynthetic process
GO:0042921 glucocorticoid receptor signaling pathway
GO:0043401 steroid hormone mediated signaling pathway
GO:0043402 glucocorticoid mediated signaling pathway
GO:0043525 positive regulation of neuron apoptotic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060603 mammary gland duct morphogenesis
GO:1900170 negative regulation of glucocorticoid mediated signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001409 Glucocorticoid receptor
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR008946 Nuclear hormone receptor, ligand-binding
PFAM PF00104
PF02155
PF00105
PRINTS PR00528
PR00047
PR00398
PIRSF
SMART SM00430
SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3HUQ5
UniProt Splice Variant
Entrez Gene 281946
UniGene Bt.9399
RefSeq NP_001193563
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020463 DAAA02020464 DQ192585 U37383
GenPept AAA80536 ABA40995

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca