InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.41314

Summary

InnateDB Protein

IDBP-699309.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.41314

Protein Name

ras-related protein Rab-7a

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000013451

InnateDB Gene

IDBG-646498 (BT.41314)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.

Predicted by orthology
Total	42 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019003	GDP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006622	protein targeting to lysosome
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007174	epidermal growth factor catabolic process
GO:0007264	small GTPase mediated signal transduction
GO:0008333	endosome to lysosome transport
GO:0015031	protein transport
GO:0045022	early endosome to late endosome transport
GO:0090383	phagosome acidification
GO:0090385	phagosome-lysosome fusion

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005764	lysosome
GO:0005770	late endosome
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0045335	phagocytic vesicle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000795 Elongation factor, GTP-binding domain
IPR001806 Small GTPase superfamily
IPR002041 Ran GTPase
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR006762 Gtr1/RagA G protein
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00009
PF00071
PF00025
PF04670
PF08477

PRINTS

PR00315
PR00449
PR00627
PR00328

PIRSF

SMART

SM00176
SM00174
SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt