InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: XRCC4

Summary

InnateDB Protein

IDBP-699333.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

XRCC4

Protein Name

DNA repair protein XRCC4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000040350

InnateDB Gene

IDBG-646520 (XRCC4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding

Biological Process

GO:0001701	in utero embryonic development
GO:0002328	pro-B cell differentiation
GO:0006266	DNA ligation
GO:0006302	double-strand break repair
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0006310	DNA recombination
GO:0007417	central nervous system development
GO:0010165	response to X-ray
GO:0010212	response to ionizing radiation
GO:0010332	response to gamma radiation
GO:0033077	T cell differentiation in thymus
GO:0033151	V(D)J recombination
GO:0033152	immunoglobulin V(D)J recombination
GO:0043524	negative regulation of neuron apoptotic process
GO:0045190	isotype switching
GO:0048146	positive regulation of fibroblast proliferation
GO:0050769	positive regulation of neurogenesis
GO:0051103	DNA ligation involved in DNA repair
GO:0051351	positive regulation of ligase activity

Cellular Component

GO:0005634	nucleus
GO:0005813	centrosome
GO:0005829	cytosol
GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex
GO:0030054	cell junction
GO:0032807	DNA ligase IV complex
GO:0070419	nonhomologous end joining complex