Version 5.4
Bos taurus Protein: BT.103700
Summary
InnateDB Protein IDBP-699334.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.103700
Protein Name hect domain and RCC1-like domain 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000053409
InnateDB Gene IDBG-646513 (BT.103700)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016874 ligase activity
Biological Process
GO:0008152 metabolic process
GO:0010507 negative regulation of autophagy
GO:0016567 protein ubiquitination
GO:0021702 cerebellar Purkinje cell differentiation
GO:0031175 neuron projection development
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0050885 neuromuscular process controlling balance
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000408 Regulator of chromosome condensation, RCC1
IPR000569 HECT
IPR001680 WD40 repeat
IPR001870 B30.2/SPRY domain
IPR003877 SPRY domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR009060 UBA-like
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
IPR017986 WD40-repeat-containing domain
PFAM PF00415
PF00632
PF00400
PF00622
PRINTS PR00633
PIRSF
SMART SM00119
SM00320
SM00449
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q862P0
UniProt Splice Variant
Entrez Gene 538029
UniGene Bt.104458
RefSeq NP_001096752
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB098939 DAAA02028744 DAAA02028745 DAAA02028746
GenPept BAC56429

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca