Version 5.4
Bos taurus Protein: SYNE2
Summary
InnateDB Protein IDBP-699598.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNE2
Protein Name spectrin repeat containing, nuclear envelope 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029285
InnateDB Gene IDBG-646766 (SYNE2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0006998 nuclear envelope organization
GO:0007097 nuclear migration
GO:0007163 establishment or maintenance of cell polarity
GO:0010761 fibroblast migration
GO:0030335 positive regulation of cell migration
GO:0031022 nuclear migration along microfilament
GO:0034504 protein localization to nucleus
GO:0051642 centrosome localization
GO:0090286 cytoskeletal anchoring at nuclear membrane
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005925 focal adhesion
GO:0016021 integral component of membrane
GO:0016235 aggresome
GO:0016529 sarcoplasmic reticulum
GO:0030016 myofibril
GO:0030018 Z disc
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031965 nuclear membrane
GO:0031981 nuclear lumen
GO:0034993 SUN-KASH complex
GO:0045111 intermediate filament cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
IPR009053 Prefoldin
IPR012315 KASH domain
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
PFAM PF00307
PF00435
PF10541
PF11971
PRINTS
PIRSF
SMART SM00033
SM00150
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MF78
UniProt Splice Variant
Entrez Gene 540504
UniGene
RefSeq NP_001193515
HUGO HGNC:17084
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02029390 DAAA02029391 DAAA02029392 DAAA02029393 DAAA02029394 DAAA02029395 DAAA02029396 DAAA02029397 DAAA02029398 DAAA02029399
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca