InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SPTB

Summary

InnateDB Protein

IDBP-699609.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SPTB

Protein Name

spectrin, beta, erythrocytic

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000006213

InnateDB Gene

IDBG-646775 (SPTB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0005543	phospholipid binding
GO:0030506	ankyrin binding
GO:0046982	protein heterodimerization activity
GO:0051015	actin filament binding

Biological Process

GO:0006779	porphyrin-containing compound biosynthetic process
GO:0007009	plasma membrane organization
GO:0030097	hemopoiesis

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0008091	spectrin
GO:0009986	cell surface
GO:0014731	spectrin-associated cytoskeleton
GO:0016020	membrane
GO:0030863	cortical cytoskeleton
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001605 Pleckstrin homology domain, spectrin-type
IPR001715 Calponin homology domain
IPR001849 Pleckstrin homology domain
IPR002017 Spectrin repeat
IPR016343 Spectrin, beta subunit
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain

PFAM

PF00307
PF00169
PF00435
PF11971

PRINTS

PR00683

PIRSF

PIRSF002297

SMART

SM00033
SM00233
SM00150

TIGRFAMs

Post-translational Modifications

Modification

Cross-References