Version 5.4
Bos taurus Protein: BT.105583
Summary
InnateDB Protein IDBP-700557.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105583
Protein Name frizzled-7
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000002946
InnateDB Gene IDBG-647759 (BT.105583)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005109 frizzled binding
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
GO:0030165 PDZ domain binding
GO:0042813 Wnt-activated receptor activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007166 cell surface receptor signaling pathway
GO:0007275 multicellular organismal development
GO:0010812 negative regulation of cell-substrate adhesion
GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
GO:0016055 Wnt signaling pathway
GO:0019827 stem cell maintenance
GO:0033077 T cell differentiation in thymus
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035412 regulation of catenin import into nucleus
GO:0035567 non-canonical Wnt signaling pathway
GO:0038031 non-canonical Wnt signaling pathway via JNK cascade
GO:0042327 positive regulation of phosphorylation
GO:0042666 negative regulation of ectodermal cell fate specification
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048103 somatic stem cell division
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0060070 canonical Wnt signaling pathway
GO:0060231 mesenchymal to epithelial transition
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000539 Frizzled protein
IPR017981 GPCR, family 2-like
IPR020067 Frizzled domain
PFAM PF01534
PF01392
PRINTS PR00489
PIRSF
SMART SM00063
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N4K7
UniProt Splice Variant
Entrez Gene 524255
UniGene Bt.105583
RefSeq NP_001137563
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02005602
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca